Intermittent fasting may help protect the brain from Alzheimer’s disease

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Bloemfontein : As the world’s population continues to age, Alzheimer’s disease is becoming increasingly common. Alzheimer’s disease is the most prevalent form of dementia. Dementia is a disease used to describe a range of symptoms associated with a decline in brain function with age. Symptoms include memory loss, communication difficulties, problem-solving struggles, and personality or behavior changes. The World Health Organization estimates that by 2050 the number of people suffering from the condition will triple. A major challenge is that Alzheimer’s is a complex condition with no known cure. However, researchers have identified several major risk factors associated with the disease. These include age, genetics, lifestyle factors and underlying medical conditions.

One of the most promising areas of research in recent years on age-related diseases such as Alzheimer’s disease has been the accumulation of harmful proteins in the brain. Amyloid in particular. Amyloid remains a major area of ​​research in Alzheimer’s disease because its increase is associated with the development of the condition. The accumulation of amyloid can lead to plaque formation. These plaques can hinder communication between brain cells. This ultimately contributes to cognitive decline and other symptoms associated with Alzheimer’s disease.

Amyloid is a large membrane protein that is essential for nerve development and repair. But in later life its contaminated form can destroy nerve cells. This leads to the loss of thought and memory that is associated with Alzheimer’s. So the researchers sought to find out whether dietary interventions, specifically intermittent fasting, would counteract the accumulation of amyloid in the brain and potentially protect against age-related brain cell death. A paper published in 2021 showed that experiments on rats found that intermittent fasting counteracted amyloid accumulation in the brain.

These findings were further confirmed in a paper published in May 2022. These findings are an important contribution to exploring the potential role of dietary interventions and are consistent with previous studies that support the idea that intermittent fasting may help counteract amyloid accumulation in the brain and protect against age-related brain cell death. Could The most recent study using a variation of intermittent fasting was published in September 2022. The clinical phase of this study is ongoing.

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